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With the 2025-25 Serie A season in just under a month, it is expected among top flight fans in Italy.
Napoli heads for upcoming campaigns as a bookmaker’s favorite to hold the title, but some clubs have a real chance to beat them.
With that in mind, before looking into the Serie A title race, take a look at the latest odds and matchday 1 fixtures.

Serie A 2025/26: Matchday 1 Fixtures
Saturday, August 23rd
Genoa vs Lecce Sassuolo vs Napoli Milan vs Cremonese Roma vs Bologna
Sunday, August 24th
Cagliari vs Fiorentina Como vs Lazio Atalanta vs Pisa juventus vs Parma
Monday, August 25th
Udinese vs Verona Inter vs Torino
Serie A 2025-26: Season Preview
Antonio Conte does a great job in his first season as manager of Napoli, fantasizing the chance to lead them to another Scudetto this season.
The board supported Conte in the summer transfer window, bringing in several new players and strengthening the already impressive team.
Centre back Sam Bekema is a wise acquisition from Bologna, and Noah Lang adds an offensive thrust after joining from PSV Eindhoven.
But the club’s outstanding signature may be Kevin de Bruin, who arrived for a free transfer after a trophy-equipped spell with Manchester City.
Napoli will be difficult to stop their quest to hold the Serie A title, but last season’s runner-up Inter can run for the money.
Christian Chive wants to replace Simone Inzagi as manager and build on the solid foundation he has left behind.

Chivu led Parma safely in his first management position last season, but he couldn’t resist the temptation to return to the club he stood out for as a player.
Inter will be active during the transfer period and expect more new arrivals at Sansilo before the deadline. They should try this season.
Juventus is also expected to be in the mix. Manager Igor Tudor has led them to Champions League qualification after replacing Thiago Motta in March and is keen to further advance.
The Turin Giants have signed several talented players this summer, including Jonathan David, who joined the club on a free transfer from the League One costume reel.

David has 146 goals and 45 assists in 315 appearances for the French Club, potentially becoming a major contender to win the Golden Boots in Serie A this season.
Rome, Milan, Atalanta and Lazio are competing for European qualifications, but no one will appeal to the title winner.
Juventus, Naples and Inter will rarely choose them at the end of the campaign, but are fantasized to fill the top three positions.
Serie A 2025-26: Complete odds
Serie A Champions Napoli’s season is a champion heading into the full market and will be a popular pick for many sports bettors.
Fans who are leaning towards bets can take advantage of the BET365 bonus code if they are betting in the title race. This is the perfect odds:
Naples – 2/1 Inter – 5/2 Juventus – 9/2 Milan – 11/2 Rome – 11/1 Atalanta – 20/1 Lazio – 33/1 Fiorentina – 66/1 Bologna – 80/1 Como – 80/1 Genoa – 500/1 Sassolo – 500/1 1000/1 Verona – 1000/1 Lecce – 1000/1 Cremonese – 1500/1 PISA – 1500/1
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